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omparative study of the efficacy of ultrasound-guided transversus abdominis plane block between using 0.125% and 0.25% of bupivacaine on postoperative opioid consumption in kidney transplant recipients

Comparative study of the efficacy of ultrasound-guided transversus abdominis plane block between using 0.125% and 0.25% of bupivacaine on postoperative opioid consumption in kidney transplant recipients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230919004
Enrollment
76
Registered
2023-09-19
Start date
2023-10-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who undergoing KT recipients surgery. Kidney transplantation, Transversus abdominis plane block, TAP block, Fentanyl consumption, Postoperative pain

Interventions

Receiving 50 mg (10 ml) of bupivacaine plus 100 mcg of adrenaline (0.1 ml) diluted in normal saline up to 20 ml for TAP block.,Receiving 25 mg (5 ml) of bupivacaine plus 100 mcg of adrenaline (0.1 ml)
Active Comparator Drug,Active Comparator Drug
0.25% group,0.125% group

Sponsors

Faculty of medicine, Khon Kaen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ESRD patients who undergoing KT recipients. 2. Age at least 18 years old 3. American society of Anesthesiologists (ASA PS) classification III-IV

Exclusion criteria

Exclusion criteria: 1. History of chronic pain 2. History of using analgesic medication within 24 hours 3. Long term usage of antidepressants, antipsychotics, anticonvulsant, clonidine at least 3 months 4. Known allergy to any study drugs 5. Pregnancy or lactation 6. Contraindicated for TAP block such as coagulopathy, skin infection 7. Unable or refusal to use IV PCA

Design outcomes

Primary

MeasureTime frame
Fentanyl consumption 24 hours postoperatively Review IV PCA machine

Secondary

MeasureTime frame
Postoperative pain score 0,6,12,18, 24 hours postoperatively NRS at rest and during movement,Complication from TAP block 24 hours postoperatively Ward nurse,Complication of opioids 24 hours postoperatively Ward nurse,Patient satisfaction 24 hours postoperatively Ward nurse

Countries

Thailand

Contacts

Public ContactPatipharn Siwakul

Faculty of Medicine, Khon Kaen University

patisi@kku.ac.th0837438875

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026