Pain after open hernia surgery in pediatric patients Hernia surgery, Pediatric patients, Pain, Ketorolac
Conditions
Interventions
1 mg/kg of intravenous ketorolac diluted in 0.9% normal saline up to 2 ml before skin incision,Giving placebo as intravenously 2 ml of 0.9% normal saline
Active Comparator Drug,Placebo Comparator No treatment
Ketorolac tromethamine,Control
Sponsors
Khon Kaen University
Eligibility
Sex/Gender
All
Age
2 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1. Children aged more than 2 years old, but less than 7 years old 2. ASA classification I-II 3. Undergoing open unilateral inguinal hernia repair
Exclusion criteria
Exclusion criteria: 1. Parents refusal 2. History of allergy to study drugs 3. History of coagulopathy or thrombocytopenia 4. History of asthma or respiratory symptoms 5. History of chronic pain condition or opioids prescription 6. History of GI bleeding or gastric pain 7. Clinically significant renal or hepatic disease: patients who have abnormal renal function and/or abnormal liver function test or have history of renal/liver disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative cumulative fentanyl consumption Intraoperative period Anesthetic record | — |
Secondary
| Measure | Time frame |
|---|---|
| - Pain score during PACU stay At at 0, 30, 60 minutes postoperatively Face, Legs, Activities, Cry, Consolability pain scale,Cumulative fentanyl consumption during PACU stay PACU stay PACU record,Intraoperative bleeding Intraoperative period Suction bottle, gauze, and swab,Incidence of opioids' side effects PACU stay Sedation score, respiratory depression, nausea and vomiting | — |
Countries
Thailand
Contacts
Public ContactPeerapong Sangsungnern
Faculty of Medicine, Khon Kaen University
Outcome results
None listed