Post COVID-19 syndrome Post COVID-19 syndrome, Prevalence,
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 60 years. 2. Experiencing at least one of the following post-COVID-19 symptoms for a duration of at least four weeks after the COVID-19 infection: fatigue, dyspnea, musculoskeletal pain, cough, headache, palpitation, decreased exercise capacity, loss of appetite, nausea, etc. 3. Have received a diagnosis of COVID-19 infection through RT-PCR or ATK testing. 4. Capable of effective communication and able to follow instructions.
Exclusion criteria
Exclusion criteria: 1. History of cardiovascular diseases. 2. History of syncope or autonomic abnormalities before COVID-19 infection. 3. Use of drugs affecting the autonomic nervous system, e.g., beta-blockers, etc. 4. Alcoholism or current smoking. 5. Pregnancy. 6. History of cleft lip and cleft palate. 7. Body temperature exceeding 37.5 degrees Celsius. 8. Unstable cardiovascular function: heart rate > 100 bpm, blood pressure < 90/60 mmHg or > 140/90 mmHg, or SpO2 less than 95%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of respiratory disorder First visit of study Borg scale, mmRc, pulmonary function test,Prevalence of neurocognitive disorder First visit of study Montreal Cognitive Assessment (MoCA) score,Prevalence of autonomic dysfunction First visit of study Deep breathing test, Head-up tilt table test, NASA 10-minute lean test,Prevalence of mental health disorder First visit of study State anxiety inventory, depression, and risk of suicide questionnaires,Prevalence of musculoskeletal disorder First visit of study Fatigue Severity Scale,Prevalence of exercise Intolerance First visit of study 1-minute sit to stand test, the modified Bruce protocol | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular responses to Head-up tilt table test and the NASA 10-minute lean test First visit of study Heart rate and blood pressure ,Exercise capacity of 1-minute sit to stand test and the modified Bruce protocol First visit of study Exercise time and time of sit-to-stand | — |
Countries
Thailand
Contacts
Mae Fah Luang University