Skip to content

Efficacy of Andrographis paniculata spray in acute pharyngitis

Efficacy of Andrographis paniculata spray in acute pharyngitis: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230915005
Enrollment
60
Registered
2023-09-15
Start date
2023-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute viral pharyngitis Andrographis paniculata, acute viral pharyngitis, sore throat, plant extract, spray

Interventions

The throat spray that contains Andrographis Paniculata extract (Invented by the research group) was prescribed to spray in the throat 2 puffs/time and 3 times a day for 5 days for patients in group A,
Experimental Drug,Active Comparator Drug
Andrographis Paniculata spray,chamomile spray

Sponsors

Abhaiphubet Chaopraya Hospital Foundation
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients (aged from 18 years old) presented in the hospital with an acute sore throat for less than 4 days were enrolled. The patients with a pain score greater than 5 out of 10 and a diagnosis of acute pharyngitis confirmed by an otolaryngologist were included in the study.

Exclusion criteria

Exclusion criteria: The exclusion criteria were positive COVID-19 test, history of allergy, intolerance, or sensitivity to any of the study medications, pregnant or lactating women, and patients who had taken antibiotics or corticosteroid less than 14 days prior.

Design outcomes

Primary

MeasureTime frame
sore throat THE FIRST DAY BEFORE INTERVENTION AND 1 to 5 DAYS AFTER INTERVENTION 11-point numeric rating scale from 0 to 10

Secondary

MeasureTime frame
difficulty swallowing THE FIRST DAY BEFORE INTERVENTION AND 1 to 5 DAYS AFTER INTERVENTION 11-point numeric rating scale from 0 to 10,cough THE FIRST DAY BEFORE INTERVENTION AND 1 to 5 DAYS AFTER INTERVENTION 11-point numeric rating scale from 0 to 10,pharyngeal erythematous mucosa THE FIRST DAY BEFORE INTERVENTION, 3 and 5 DAYS AFTER INTERVENTION severity scale 0 to 3,pharyngeal swelling mucosa THE FIRST DAY BEFORE INTERVENTION, 3 and 5 DAYS AFTER INTERVENTION severity scale 0 to 3

Countries

Thailand

Contacts

Public ContactRisa Okonogi

Chiangrai Prachanukroh Hospital

risa.oko@cpird.In.th0947423555

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026