Asthmatic patients have stable symptoms with the ability to perform step aerobics training and breathing exercise. Asthma, Step aerobics, Inflammation
Conditions
Interventions
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who will be diagnosed to be moderate to severe asthma according to Global Initiative for Asthma 2. Age 18-65 years 3. Non regular exercise (less than 3 times/week and less than 30 min/day) 4. Patients will require to receive stable dose of asthma medications throughout the study.
Exclusion criteria
Exclusion criteria: 1. Other respiratory diseases such as chronic obstructive pulmonary disease, chronic respiratory failure, and respiratory infections. 2. Asthma exacerbation within 1 month 3. Congestive heart failure, chest pain from myocardial ischemia 4. Condition with musculoskeletal disorders affecting the movement of the shoulder or knee, or ankle joints. 5. Presence of orthopedic or neuromuscular conditions interfering with the ability to perform step aerobic exercise such as herniated disc, lumbar stenosis, and muscle weakness 6. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Airway inflammation Pre-test, Intermediate-test, and post exercise training The fractional concentration of exhaled nitric oxide by using a FeNo Vivatmo Pro,Asthma control Pre-test, Intermediate-test, and post exercise training Asthma Control Test (ACT), Asthma Quality of Life (AQLQ), and Asthma Control Questionnaire (ACQ) | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung function Pre-test, Intermediate-test, and Post exercise training Respiratory muscle strength test, and pulmonary function test,Physical fitness Pre-test, Intermediate-test, and Post exercise training One leg stand test, Timed-up and Go test , 10- meter walk test , and Five time sit to stand test ,Exercise capacity Pre-test, Intermediate-test, and Post exercise training 6-minute walk test,Systemic inflammation Pre-test, Intermediate-test, and Post exercise training Interleukin-5 level, Blood eosinophil count, The high-sensitivity C-reactive protein (hsCRP) | — |
Countries
Thailand
Contacts
Faculty of Medicine, Khon Kaen Universtiy, Thailand