Post operative sore throat post operative sore throat budesonide EMLA
Conditions
Interventions
Patients will receive aerosolized budesonide suspension 500 microgram via nebulization 10-minutes prior to endotracheal intubation,2.5 ml (2.5 gm) of EMLA (Eutectic mixture of local anaesthetic: 2.5%
2.5% prilocaine) cream will be applied over the endotracheal tube (ETT) cuff and its distal portion prior to endotracheal intubation.,Patients will not receive any of the intervention i.e. aerosolize
Budesonide ,EMLA,Control
Sponsors
Department of Anaesthesia,Batra Hospital & Medical Research Centre, New Delhi, India
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years. 2. ASA physical status I and II. 3. Patients undergoing elective surgeries requiring endotracheal intubation
Exclusion criteria
Exclusion criteria: 1. Anticipated difficult airway. 2. Requiring more than 2 intubation attempts. 3. Known allergy to local anaesthetic drug. 4. Recent history of steroid or non-steroidal anti-inflammatory drug use 5. Systemic illness with presenting complaints of sore/dry throat (diabetics with polydipsia, hypertensives on diuretics, moribund bed ridden patients). 6. History of airway related morbidity (post operative sore throat [POST]) 7. Patients undergoing head and neck, intraoral/nasal surgery, or recent history of such surgery. 8. Surgery in prone position 9. Ongoing upper and lower respiratory tract inflammation/infection. 10. Patients requiring post operative mechanical ventilation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post operative sore throat (POST) At 2 hours, 6 hours, and 24 hours postoperatively Assessed using a 4-point scale: '0' no sore throat to '3' severe sore throat. | — |
Secondary
| Measure | Time frame |
|---|---|
| Post operative cough At 2 hours, 6 hours, and 24 hours postoperatively Assessed using a 4-point scale: '0' no cough to '3' severe cough. ,Post operative Hoarseness At 2 hours, 6 hours, and 24 hours postoperatively Assessed using a 4-point scale: '0' mild hoarseness to '4' severe hoarseness.,Peri-intubation haemodynamics From 5- minutes prior to induction of anaesthesia till 5-minutes post intubation of trachea heart rate (beats per minute), systolic blood pressure (mmHg), diastolic blood pressure (mmHg), and mean arterial pressure (mmHg) will be measured | — |
Countries
India
Contacts
Public ContactMamta Sethi
Batra Hospital & Medical Research Centre
Outcome results
None listed