Fragility hip fractures Fragility hip fractures, gut microbiota
Conditions
Interventions
Osteoporotic hip fracture with CKD patients,Osteoporotic hip fracture with Non-CKD patients
Other,Other
CKD patients,Non-CKD patients
Sponsors
Faculty of medicine research fund
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The patients that older than 50 years 2. The patients that have been diagnosed with Osteoporotic hip fracture, caused by falling on the ground or low energy trauma.
Exclusion criteria
Exclusion criteria: 1. The patients that diagnosed with pathologic hip fractures 2. The patients that diagnosed with multiple fracture 3. The patients that received antibiotic drugs in 90 days before the admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota's genetic extraction from patient's feces Before patient is get the surgery Feces extraction by using QIAGEN. PCR amplification and sequencing for amplify microbial 16S rRNA gene. Identify by using QIIME2 package. Classify for analysis by using scikit-learn naive Bayes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between gut microbiota profiles and metabolic bone parameters in the osteoporotic hip fracture patients with CKD and without CKD. Before patient is get the surgery Feces extraction by using QIAGEN. PCR amplification and sequencing for amplify microbial 16S rRNA gene. Identify by using QIIME2 package. Classify for analysis by using scikit-learn naive Bayes. | — |
Countries
Thailand
Contacts
Public ContactNitchanant Kitcharanant
Department of Orthopaedics, Chiang Mai University
Outcome results
None listed