Efficacy of local Bupivacaine injection of post-operative pain in Endoscopic sinus surgery Bupivacaine, post-operative pain, Endoscopic sinus surgery
Conditions
Interventions
local 0.5% Bupivacaine injection, dose 1:1, 10 ml at sinus mucosa ( 2.5 ml Lt anterior ethmoid , 2.5 ml at Lt Sphenopalatine , 2.5 ml Rt anterior ethmoid , 2.5 ml at Rt Sphenopalatine ),NSS 10 ml at s
Experimental Drug,Experimental Drug
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1 Aged18 -75 year 2 ASA physical status I - III 3 Defining CRS + bilateral FESS
Exclusion criteria
Exclusion criteria: 1 Patients with clinically significant cardiovascular, pulmonary, hepatic or neurologic disease. 2 Allergy to bupivacaine, lidocaine, or epinephrine 3 Potentially increased anesthetic or analgesic requirements (e.g. chronic alcohol or opioid use) 4 Taking over the-counter pain medications within 48 hours of scheduled surgery 5 Patients who are unable to understand the questionnaires or the visual analog scale (VAS) pain scores 6 Pregnancy 7 Patient requiring additional procedures involving septum, rhino or turbinate were excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post operative pain score 1 , 2 , 4 , 6 , 8 , 12 , 24 hr VAS score | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative rescue analgesics 1day post operation Amount and first time to used,Complication post-op ESS between Bupivacaine group and control group 1day Post operation Number of complication post-op ESS,Side effect of Bupivacaine group in ESS 1day Post operation Show Side effect | — |
Countries
Thailand
Contacts
Public Contactwiracha Leewannapasai
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed