Root coverage outcomes of subepithelial connective tissue grafts harvesting from palate before and after recipient site preparation. Viability of palatal subepithelial connective tissue graft harvests. Root coverage outcomes Graft viability Subepithelial connective tissue grafts
Conditions
Interventions
Subepithelial connective tissue grafts harvesting from the palate after recipient site preparation ,Subepithelial connective tissue grafts harvesting from the palate before recipient site preparation
Experimental Procedure/Surgery,Experimental Procedure/Surgery
Sponsors
Faculty of Dentistry, Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Part I - Age more than 18 years old who needs a periodontal soft tissue graft treatment - No contra-indicatory to the surgery - Single gingival recession at buccal sites of single root teeth classified as RT1 or RT2 by Cairo, 2011 - Good inflammation control (full-mouth bleeding on probing less than 25%) - Good plaque control (full-month plaque score less than 25%) - Probing depth less than 4 mm at an interesting site - No history of periodontal surgery at the recipient site Part II - Age more than 18 years old who needs a periodontal soft tissue graft treatment - No contra-indicatory to the surgery.
Exclusion criteria
Exclusion criteria: Part I - Patients who have medical contraindications to periodontal surgery - Taking antibiotics or drugs affecting periodontal healing within 6 months. - Excessive tooth mobility on the surgical site - Recession defect with restoration/demineralization/caries/deep abrasion or abfraction >1mm or evidence of pulpal pathology Part II - Patients who have medical contraindications to periodontal surgery - Patients who have a disease or syndrome and receive medications that affect the quantity of saliva, inflammation phase, and healing process. These include the patients who are diagnosed with xerostomia or Sjogren's syndrome; patients who take chemotherapy drugs, antiresorptive drugs, antiangiogenics drugs, steroid drugs, anti-inflammatory drugs (depending on the type of drugs, e.g., ibuprofen is eliminated in 24 hours, thus patients who take ibuprofen >24 hours before the surgery can be included), antibiotic drugs in past 6 months, immunosuppressive drugs, amphetamine/methamphetamine drugs; and patients who currently use marijuana or a current smoker. - The biopsy site has inflamed gingival tissue (redness, swelling, or bleeding), involves an important organ at the palate, or presents any pathologic oral lesions. - The patients undergo a soft tissue graft harvesting but the harvesting site is insufficient for another 4-mm diameter 2-mm thick biopsy sample, e.g., the area is closed to some vital structures, thin palatal tissue < 2 mm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gingival recession reduction 3 months measurement with probe and intraoral scanner (mm) | — |
Secondary
| Measure | Time frame |
|---|---|
| viability of SCTG 24 hours Prestoblue viability assay | — |
Countries
Thailand
Contacts
Public ContactKaewkwan Tanthai
Faculty of Dentistry, Mahidol University
Outcome results
None listed