Healthy male volunteers aged between 20-35 years old Cryptolepis buchanani stem, Entanoids muscle relaxing oil, muscle soreness.
Conditions
Interventions
This study was a randomized, placebo-controlled, clinical trial and was bipartisan, (double-blinded) by concealing the volunteers, investigators, statistician and research team. The volunteers will be
Experimental Other,Active Comparator Drug,Placebo Comparator Other
Efficacy of Thao En On and Phlai extract spray for delayed onset muscle soreness after elbow flexors exercise,Efficacy of diclofenac spray ,Efficacy of placebo
Sponsors
Center of Excellence for Innovation in Chemistry (PERCH-CIC)
Eligibility
Sex/Gender
Male
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Male 2. Aged between 20-35 years old 3. Having a normal body mass index (Body mass index = 18.5-24.9 kg/m2). 4. Having low level of physical activity after testing the Global Physical Activity Questionnaire (GPAQ). 5. Having no pain and problems in the musculoskeletal system of the study arm. 6. Exercise or play sport less than 2 times/week 7. Not practicing resistance exercises for increasing muscle strength at least 6 months before participating the study 8. Do not have a regular job that requires lifting force, such as a parcel delivery worker or fitness trainer 9. No history of congenital disease such as heart disease, blood pressure, diabetes, muscle and joint disease, cancer, allergies or history of allergy to anti-inflammatory drugs, etc. 10. Having no restriction on the movement of the joints of the forearm limbs 11. No history of allergies to chemicals, drugs, muscle massage creams, pain relief sprays, and alcohol. 12. Do not take pain-relieving drugs or receive pain-relieving treatments such as acupuncture, physical therapy, Thai therapeutic massage in the last 3 months 13. Be able to exercise with resistance 14. Pass the Pre-Exercise Readiness Assessment (PAR-Q). 15. Subjects were willing to participate in the study after being informed of the objectives, methods, risks, and outcomes of the study and consented to comply with the experimental guidelines throughout the period of operation before starting the experiment All subjects must sign a voluntary consent form.
Exclusion criteria
Exclusion criteria: 1. Having history of sensitive skin (hyperallergic reaction) 2. Severe disorders of the musculoskeletal system, joints and bones 3. Having a clearly visible abnormality of the joints such as shoulder joints, elbow joints, wrist deformities 4. Having limitations of the body in exercising by lifting weights. 5. Not able to participate the study throughout the duration of the research project for 5 consecutive days. 6. Having history of eczema or psoriasis or infectious dermatitis on the arm. 7. Taking oral medications, steroid injections, antibiotics, non-steroidal anti-inflammatory drugs, or antihistamines during the 5-day period while participating in the study. 8. Having history of major surgery on the arm within 1 year. 9. Having a history of skin cancer within 1 year 10. having wounds, open wounds or blisters on the arm 11. Having a history of allergic reactions to herbs/other substances. The ingredients of the product, such as Plai, Tao En-on, borneol, menthol, eucalyptus, camphor, alcohol and diclofenac.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual pain scale 4 days Measured the soreness by Universal goniometer and WE-algometer | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactNeti Waranuch
Faculty of Pharmaceutical sciences, Naresuan university, Thailand
Outcome results
None listed