The effects of milk of magnesia for prevention post-operative ileus after hysterectomy: A randomized controlled trial

Status

Unknown

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230816005

Enrollment

160

Registered

2023-08-16

Start date

2023-09-25

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who have undergone hysterectomy, including both open abdominal and laparoscopic procedures Milk of magnesia, Hysterectomy, Post operative ileus

Interventions

The standard treatment after hysterectomy, following the ERAS (Enhanced Recovery After Surgery) protocol 1. Encouraging the patient to start drinking water within 3-6 hours after surgery (counting fro

No Intervention No treatment,Experimental Drug

Arm 1,Arm 2

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age more than 18 years old 2. All patients who have undergone hysterectomy, including both open abdominal and laparoscopic procedures.

Exclusion criteria

Exclusion criteria: 1. History of allergy to milk of magnesia or any other ingredients listed on the medication label. 2. Presence of any underlying medical conditions that contraindicate the use of milk of magnesia. 3. Presence of fever or evidence of infection prior to surgery. 4. Diagnosis of intestinal obstruction, GERD, evidence of gastric ulcers from endoscopic examination, or chronic constipation. 5. History of radiation therapy at pelvic or abdominal region. 6. Pregnant and requiring hysterectomy, such as for cervical cancer or post cesarean hysterectomy, due to the presence of delayed gastric emptying time during pregnancy. 7. Injury to adjacent organs during hysterectomy, requiring the patient to abstain from food and water. 8. Severe complications from a surgical procedure that require treatment in the Intensive Care Unit (ICU). 9. Unable to read or speak Thai language. 10. Impaired or incomplete consciousness or having a neurological or psychiatric disorder.

Design outcomes

Primary

Measure	Time frame
The average duration after hysterectomy until resolved bowel function after skin closed hours/days	—

Secondary

Measure	Time frame
Time and Quantity of solid diet that patient can consume after hysterectomy after skin closed hours/days	—

Countries

Thailand

Contacts

Public ContactWathirada Karnchanabanyong

Faculty of Medicine, Siriraj Hospital, Mahidol University

fwathirada@gmail.com0837744409

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026