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The study of metabolite profile in diabetic kidney disease using metabolomic approaches

The study of metabolite profile in diabetic kidney disease using metabolomic approaches

Status
Unknown
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20230815003
Enrollment
510
Registered
2023-08-15
Start date
2023-10-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic kidney disease (DKD) in different stages compared to diabetic patients without abnormal kidney function. Metabolomic, DKD, DM

Interventions

Diabetic patients with normal kidney function as a disease control group,Diabetic patients with eGFR greater than 90 ml per min per 1.73 m2 with albuminuria (Micro or Macro),Diabetic patients with eGF
Group 1,Group 2,Group 3,Group 4,Group 5

Sponsors

Faculty of Medicine Siriraj Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. DM patients and DKD patients who are above 18 years old. 2. Patients receiving non-dialysis treatment. 3. Patients who are not pregnant or breastfeeding. 4. DM patients and DKD patients who have undergone DM screening laboratory tests, such as eGFR and albuminuria, within the past year

Exclusion criteria

Exclusion criteria: 1. Patients with kidney disease from other causes. 2. Patients with acute kidney injury. 3. Patients diagnosed with infections or other types of cancer have not completed the treatment process. 4. Patients with incomplete or inadequate data in the database for proper analysis.

Design outcomes

Primary

MeasureTime frame
Metabolomic data of DKD 12 months Metabolomic data and correlation

Secondary

MeasureTime frame
Microbiome of DKD in diferrent stgaes 12 months 16S sequencing analysis

Countries

Thailand

Contacts

Public ContactThatsaphan Srithongkul

Faculty of Medicine Siriraj Hospital, Mahidol University

thatsaphan.sri@mahidol.ac.th0819177220

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026