Severe preeclampsia Preeclampsia
Conditions
Interventions
Magnesium Sulfate administration of an initial dose of 4 grams intravenously given bolus within 15 minutes, followed by an intravenous maintenance dose of 1-2 grams per hour until 12 hours.,Magnesium
Active Comparator Drug,Active Comparator Drug
Magnesium Sulfate 12 hours Maintenance,Magnesium Sulfate 24 hours Maintenance
Sponsors
Local, in Arifin Achmad Hospital
Eligibility
Sex/Gender
Female
Age
17 Years to 43 Years
Inclusion criteria
Inclusion criteria: All pregnant women diagnosed with severe preeclampsia who are eligible for magnesium sulfate administration get a loading dose of magnesium sulfate Zuspan. Postpartum severe preeclampsia mothers who received a maintenance dose of magnesium sulfate Zuspan.
Exclusion criteria
Exclusion criteria: All severe preeclampsia patients with decreased consciousness; had complications such as eclampsia, HELLP syndrome, kidney failure, or acute pulmonary edema; were in labor; received antihypertensive therapy in the last 12 hours; had an allergy to the trial drugs; and had asthma and heart disease were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal Outcome 42 days Direct assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| Side Effects and Clinical Symptoms of MgSO4 Toxicity 24 hours Interview and Direct assessment | — |
Countries
Indonesia
Contacts
Public ContactDonel Suhaimi
Fakultas Kedokteran Universitas Riau
Outcome results
None listed