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Therapeutic Effects of Exercise Combined Low-Level LASER Therapy on Patients with Peripheral Artery Disease plus Diabetic Foot Ulcer

Therapeutic Effects of Exercise Combined Low-Level LASER Therapy on Patients with Peripheral Artery Disease plus Diabetic Foot Ulcer

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230810003
Enrollment
26
Registered
2023-08-10
Start date
2021-03-08
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with Peripheral Artery Occlusive Disease plus Diabetic Foot Peripheral Artery Occlusive Disease, Diabetic Foot

Interventions

Resistance exercise and functional activity training. The exercise frequency was twice to 5 times per week and four weeks of treatment.,Resistance exercise and functional activity training. The exerci
Exercise,Exercise plus LLLT

Sponsors

Ministry of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Diagnosis of T2D 2. PAD was diagnosed by an angiogram, duplex ultrasonography, or ankle-brachial blood pressure index (ABPI) 3. The ulcer is located on the lower extremity 4. The ulcer is present for a minimum of 2 weeks during which it has been ei-ther stable or worsening

Exclusion criteria

Exclusion criteria: 1. Evidence of acute cellulitis and osteomyelitis in the affected extremity 2. Presence of any of one or more medical conditions including hepatic, hemato-logic, or immune disease 3. Presence of malignant disease not in remission for more than 5 years 4. Use of oral or parenteral corticosteroids, immunosuppressive, or cytotoxic agents 5. Pregnancy

Design outcomes

Primary

MeasureTime frame
wound size before (T0), 2 weeks (T1), and 4 weeks (T2) measured by image J software. ,wound classification before (T0), 2 weeks (T1), and 4 weeks (T2) Wagner classification,Sensation before (T0), 2 weeks (T1), and 4 weeks (T2) Semmes Weinstein monofilament examination ,walking distance before (T0), 2 weeks (T1), and 4 weeks (T2) 6 minute walking test,quality of life before (T0), 2 weeks (T1), and 4 weeks (T2) SF-36,pain before (T0), 2 weeks (T1), and 4 weeks (T2) VAS

Secondary

MeasureTime frame
Skin temperature immediate after intervention infrared thermography

Countries

Taiwan

Contacts

Public ContactYu Jung Cheng

China Medical University

s5888116@gmail.com0921922335

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026