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A randomized, investigator blind, split-face study of the efficacy of using Eucerin Dermopure to reduce mucocutaneous side effects of adapalene/benzoyl peroxide combination (Epiduo) for the treatment of acne vulgaris.

A randomized, investigator blind, split-face study of the efficacy of using Eucerin Dermopure to reduce mucocutaneous side effects of adapalene/benzoyl peroxide combination (Epiduo) for the treatment of acne vulgaris.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230810001
Enrollment
40
Registered
2023-08-10
Start date
2021-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient with acne vulgaris. Eucerin Dermopure, irritation, mucocutaneous side effects, acne treatment, acne vulgaris

Interventions

The skincare formulation combines Licochalcone A, Sympsitive, Panthenol, Ceramides. ,The skincare formulation includes Cetyl alcohol, Stearic acid, Glyceryl Monostearate, Propylene Glycol, Propyl Para
Active Comparator Other,Active Comparator Other
Eucerin dermapure ,Hydrophillic cream base

Sponsors

Beiresdorf Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Healthy patients with all severity grades of acne vulgaris

Exclusion criteria

Exclusion criteria: 1. Patients with concurrent facial skin infections 2. History of allergy to the study product components.

Design outcomes

Primary

MeasureTime frame
Biophysical changes of skin baseline, 2 weeks, 4 weeks using Corneometer, Tewameter, and Visia

Secondary

MeasureTime frame
Patients' assessment score baseline, 2 weeks, 4 weeks grade 0, none; grade 1, mild; grade 2, moderate; grade 3, severe. , Investigator Global Assessment baseline, 2 weeks, 4 weeks investigator global evaluation acne (IGEA) ,Acne lesion counting baseline, 2 weeks, 4 weeks Inflammatory and non-inflammatory acne counting number,Patients' satisfaction score 4 weeks grade 0, minimum; grade 10, maximum.

Countries

Thailand

Contacts

Public ContactPawinee Rerknimitr

Faculty of Medicine, Chulalongkorn University

Pawinee.R@chula.ac.th66816291862

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026