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Clinical Efficacy of Andrographis paniculata Extracted Scrub Compared With 4% Chlorhexidine Scrub in Burn Wounds: A Prospective Randomized Controlled Trial

Clinical Efficacy of Andrographis paniculata Extracted Scrub Compared With 4% Chlorhexidine Scrub in Burn Wounds: A Prospective Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230809005
Enrollment
23
Registered
2023-08-09
Start date
2019-06-03
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

second degree burn Andrographis paniculata wound cleansing second degree burn

Interventions

Andrographis and Perilla oil liquid soap (AP soap) for wound scrub. Then proceed with standard burn wound care,4% Chlorhexidine-treated for wound scrub. Then proceed with standard burn wound care
AP soap,4% Chlorhexidine

Sponsors

Faculty of Medicine Siriraj Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 18 and 60 years of age superficial second degree burns within 24 hours of sustaining the injury burn wounds covered areas at least 20% of the total body surface area (TBSA).

Exclusion criteria

Exclusion criteria: diabetes mellitus, end-stage renal disease, post-radiation therapy, immunosuppressive drug use, or immunocompromised diseases

Design outcomes

Primary

MeasureTime frame
Healing rate wound closure epithelialization

Secondary

MeasureTime frame
analgesic effect and moisturization every day pain score

Countries

Thailand

Contacts

Public ContactSuttipong Tianwattanatada

Faculty of Medicine Siriraj Hospital, Mahidol University

suttipong.tian@gmail.com0854419591

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026