Effects of Exergame with Different Motor Priming Strategies on Turning and Postural Stability in Individuals with Chronic Stroke

Effects of Virtual Reality with Different Motor Priming Strategies on Turning and Postural Stability in Individuals with Chronic Stroke

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230727001

Enrollment

Registered

2023-07-27

Start date

2023-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Turning difficulties has been reported in patients with stroke, but effective interventions for improving turning ability are limited. stroke, turning, priming, exergame

Interventions

Participants in the MI group will receive one-on-one sessions comprising 10-15 minutes of MI followed by 30-40 minutes of exergame training for a total of 12 sessions over a 4 to 6-week period by a ph

Experimental Other,Experimental Other,Sham Comparator Other

Motor imagery (MI) group,tDCS goup,Sham tDCS group

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) 6 months post first-ever stroke with unilateral motor deficits, (2) the ability to walk 10 meters independently with or without the use of walking aids, (3) a Brunnstrom stage of affected lower extremity equal or greater than 3, and (4) a score of at least 24 on the mini-mental state examination (MMSE).

Exclusion criteria

Exclusion criteria: (1) unstable medical conditions, (2) any history of other diseases known to interfere with participation in the study and (3) history of virtual games used for treatment in the past 3 months, (4) those who are allergic to patches or gels.

Design outcomes

Primary

Measure	Time frame
Turning performance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Timed Up and Go test and the 180 degree turn test,Postural stability The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Standing and reaching,Plasma biomarkers The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Brain-derived neurotrophic factor, abeta and tau	—

Measure

Time frame

Turning performance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Timed Up and Go test and the 180 degree turn test,Postural stability The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Standing and reaching,Plasma biomarkers The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Brain-derived neurotrophic factor, abeta and tau

—

Secondary

Measure	Time frame
Straight-walking performance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Walk straight for 10 meters at a comfortable speed,Balance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Berg Balance scale ,Functional gait performance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Functional Gait Assessment	—

Measure

Time frame

Straight-walking performance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Walk straight for 10 meters at a comfortable speed,Balance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Berg Balance scale ,Functional gait performance The day before the intervention (pre), the day after the conclusion of the intervention (post), and the 30th day after completing the intervention (follow-up) Functional Gait Assessment

—

Countries

Taiwan

Contacts

Public ContactSang Yi Lin

MacKay Medical College

lin31@mmc.edu.tw886226360303

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026