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Effects of Intraoperative Placement of Tetracycline, Tetracycline + Gelatin Sponge, and Placebo on Postoperative Dry Socket Incidence After Mandibular Molar Extraction (A Comparative Prospective Study)

Effects of Intraoperative Placement of Tetracycline, Tetracycline + Gelatin Sponge, and Placebo on Postoperative Dry Socket Incidence After Mandibular Molar Extraction (A Comparative Prospective Study)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230724006
Enrollment
90
Registered
2023-07-24
Start date
2021-12-29
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry socket incidence Dental extraction, dry socket, dental pain, mandibular molar extraction

Interventions

the tetracycline is a well known drug for its spectrum and bacteriostatic effect
Experimental Drug
tetracycline

Sponsors

self-funded
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients over 18 years of age. 2.Absence of general medical contraindications for oral surgery procedures such as jaws pathology, uncontrolled diabetes, uncontrolled hypertension. 3.Mandibular molar teeth indicated for extraction.

Exclusion criteria

Exclusion criteria: 1. Patients who were immunocompromised, with systemic disease, pregnant or lactating women. 2. Patients with acute or chronic infection. 3. Teeth with periapical cyst. 4. Patients allergic to tetracycline. 5. Poor compliance. 6. Mandibular molars requiring surgical extractions (either sectioning or flap releasing). 7. Impacted mandibular third molar.

Design outcomes

Primary

MeasureTime frame
dry socket 7th day after extraction VAS

Secondary

MeasureTime frame
job stress 2 month nursing stress scale, which was designed by Gary Taft and Anderson in 1981 ,Job stress 2 months T test

Countries

Iraq

Contacts

Public Contactmohammad mohammad

baghdad university

speedm88@yahoo.com7724047511

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026