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Optimizing Glycemic Control after Cardiac Surgery: A Trial of Protocol-Guided Nurse-Directed Versus Physician-Directed Insulin Adjustment: NUSULIN Trial

Efficacy of Insulin Infusion Protocol in Diabetic Patients after Cardiac surgery

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230719001
Enrollment
56
Registered
2023-07-19
Start date
2023-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Efficacy of insulin infusion protocol in blood glucose control after cardiac surgery. Insulin, Infusion, Post cardiac surgery, Intensive care

Interventions

After finishing cardiac surgery, the patient will be transferred to the ICU. Blood glucose is checked via blood drawn from arterial line. The patient will received continuous insulin infusion. Insuli
s insulin infusion protocol which is reported by Olansky et al (Journal of Diabetes Science and Technology 2009). The protocol is a computerized model that ICU nurses can practice according to easily
s order 3.Serum elec
Experimental Other,Active Comparator Other
Paper-based insulin adjustment protocol ,Insulin adjustment per surgeon&#039
s order

Sponsors

Faculty of medicine, Naresuan University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective open-cardiac surgery with cardiopulmonary bypass and 2. Age 20-90 years and 3. Established diagnosis of diabetes mellitus type2

Exclusion criteria

Exclusion criteria: Patients who underwent closed cardiac surgery Patients undergoing emergency surgery.

Design outcomes

Primary

MeasureTime frame
Efficacy of insulin protocol 0-72 hours after cardiac surgery Percentage of time blood glucose level remaining within target range

Secondary

MeasureTime frame
Safety and feasibility of insulin protocol 0-72 hours after cardiac surgery 1. Time to target of glucose less than 150 mg/dL 2. Glycemic variability 3.Numbers of hypo/hyperkalemic events 4.Numbers of protocol violation by ICU nurse

Countries

Thailand

Contacts

Public ContactNisit Poolthananant

Faculty of medicine, Naresuan University Hospital

nisitpo@nu.ac.th055965196

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026