Term pregnancy patient who schedule for cesarean delivery under spinal anesthesia Cesarean delivery Spinal hypotension Hypotension prediction index
Conditions
Interventions
Norepinephrine bolus is administered based on hypotension prediction index as a proactive treatment,Norepinephrine infusion is administered 0.05mcg kg min immediate after spinal anesthesia.
Interim
Prevention,Prevention
HPI group,NIBP group
Sponsors
Ramathibodi hospital, Mahidol University
Edward life Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Term singleton pregnancy 2. Elective cesarean delivery 3. American Society of Anesthesiology classification 2 or 3
Exclusion criteria
Exclusion criteria: 1. Hypertensive disorder 2. Gestational age less than 37 wks 3. failed spinal anesthesia 4. Cardiovascular disorder and contraindication for spinal anesthesia 5. Contraindication for finger cuff Acumen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of spinal hypotension 10 minute after delivery incidence | — |
Secondary
| Measure | Time frame |
|---|---|
| Time weighted average MAP less than 65 mmHg end of surgery area under the curve,AUC MAP less than 65 mmHg-min end of surgery Area under the curve,Duration of MAP less than 65 mmHg end of surgery time,Time weighted average MAP less than 55 mmHg end of surgery area under the curve,AUC MAP less than 55 mmHg end of surgery area under the curve,Duration of MAP less than 55 mmHg end of surgery time | — |
Countries
Thailand
Contacts
Public ContactLisa Sangkum
Ramathibodi hospital, Mahidol university
Outcome results
None listed