Comparison of bronchodilator nebulization via high flow oxygen therapy and jet nebulization in acute asthma exacerbation children; A randomized controlled study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230707006

Enrollment

Registered

2023-07-07

Start date

2023-03-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

An acute severe asthma exacerbation in children aged 2-15 years severe asthma exacerbation, HFNC, high flow nasal cannulas, nebulization

Interventions

bronchodilator nebulization via HFNC (1 LPM/kg of body weight),bronchodilator nebulization via jet nebulizer which is standard of care of asthma treatment.

Experimental Device,Active Comparator Device

inline HFNC,jet nebulization

Eligibility

Sex/Gender

All

Age

2 Years to 15 Years

Inclusion criteria

Inclusion criteria: children with severe asthma exacerbation who has asthma score > 4 after initial treatment with asthma exacerbation protocol.

Exclusion criteria

Exclusion criteria: chronic lung disease, congenital heart disease, neurological deficit, craniofacial anomaly

Design outcomes

Primary

Measure	Time frame
clinical improvement 2 hours of initial treatment asthma score	—

Secondary

Measure	Time frame
bronchodilator use 24 hours after initial treatment amount of bronchodilator doses,oxygen day from initial to day without oxygen day of oxygen use,length of stay initial to day of discharge length of stay	—

Countries

Thailand

Contacts

Public ContactAraya Satdhabudha

Faculty of medicine, Thammasat university, Thailand

araya221@gmail.com0813414900

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026