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Changes in the cardiac index to predict fluid responsiveness during Trendelenburg maneuver among patients with poor tissue perfusion under mechanical ventilation with spontaneous breathing activity in surgical intensive care units

Changes in the cardiac index to predict fluid responsiveness during Trendelenburg maneuver among patients with poor tissue perfusion under mechanical ventilation with spontaneous breathing activity in surgical intensive care units

Status
Unknown
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20230704005
Enrollment
68
Registered
2023-07-04
Start date
2023-07-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who are admitted to surgical ICUs Intensive care unit

Interventions

the change of cardiac index during the Trendelenburg maneuver and fluid responsiveness in patients who required mechanical ventilation with spontaneous breathing activity in a surgical ICU, in which f
Health Services Research
the change of cardiac index

Sponsors

Faculty of Medicine Siriraj Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients who are admitted to surgical ICUs aged of more than 18 years old 2.Receiving invasive mechanical ventilation with spontaneous breathing activity 3.Richmond Agitation-Sedation Scale of less than +1 4.Present any signs of inadequate tissue perfusion which are 4.1 MAP of less than 65 mmHg 4.2 HR of more than 100 bpm 4.3 Urine output of less than 0.5 ml/kg/h 4.4 Skin mottling or capillary refilling time of more than 2 seconds 4.5 Serum lactate of more than 1

Exclusion criteria

Exclusion criteria: 1. Patient who refuses to participate in research. 2. Known or suspected increased intracranial or intra-ocular pressure 3. Absolute contraindication of radial artery cannulation 4. Persistent arrhythmias 5. Known severe valvular dysfunction, pulmonary hypertension, or LVEF less than 30% 6. Present signs of cardiogenic pulmonary edema 7. Intra-abdominal hypertension 8. Open thorax 9. Known obstruction or thrombosis of the inferior vena cava or any great veins of the lower limb 10. Lower limb amputation above ankle level 11. Received muscular relaxant agents 12. Pregnancy

Design outcomes

Primary

MeasureTime frame
performance of the change of cardiac index The outcome will be analyzed after finished AUROC, sensitivity, specificity

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactNattachai Hemtanon

Faculty of Medicine Siriraj Hospital

nattachaihem@gmail.com0656351622

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026