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Comparing Lidocaine Nasal Drop and Placebo for Decrease Discomfort and Complication of Nasogastric Tube Insertion in Thammasat University Hospital: A Randomized Controlled Trial Study

A Double-blind Randomized Controlled Trial Study Comparing Lidocaine Nasal Drop and Placebo before Nasogastric Tube Insertion in Thammasat University Hospital

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230704004
Enrollment
126
Registered
2023-07-04
Start date
2021-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Discomfort and Complication of Nasogastric Tube Insertion Nasogastric tube insertion, Lidocaine nasal drop

Interventions

Lidocaine in 2% concentration was used to applied nasally 3 minutes before NG tube insertion,Normal saline was used to applied nasally 3 minutes before NG tube insertion
Experimental Drug,Placebo Comparator Drug
Lidocaine Nasal Drop,Placebo

Sponsors

Faculty of medicine, Thammasat University, Pathumthani, Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who were more than 18 years old and indicated for nasogastric tube insertion (Gastrointestinal bleeding, Gastrointestinal obstruction, Enteral feeding, Severe vomitting, Post operative status)

Exclusion criteria

Exclusion criteria: [Patients who were the inability to answer questions due to alteration of consciousness or language problems, Patients who were the anatomical defects from ear/nose/throat regions that might cause difficulty in NG insertion, Patients who were signs and symptoms of coagulopathy, Patients who were history of lidocaine allergy, Patients with unstable hemodynamics due to Systolic blood pressure (< 90 mmHg) or Pulse rate (> 120/min) or Respiratory rate (> 30/min), Patients who were intoxicated]

Design outcomes

Primary

MeasureTime frame
Pain score At 10 minutes after end of the intervention Visual analog scale

Secondary

MeasureTime frame
Duration of procedure , The successful insertion , Complications At end of the intervention Record by case record form

Countries

Thailand

Contacts

Public ContactTuadpong Thangthong

Thammasat University Hospital

tuadpong@staff.tu.ac.th0832517059

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026