chronic knee pain in patients who have a diagnosis of knee osteoarthritis, underwent simultaneous total knee arthroplasty Genicular nerve infiltration Periarticular injection Total knee arthroplasty Total knee replacement
Conditions
Interventions
Standard total knee arthroplasty without intraoperative local anesthetic injection,Standard total knee arthroplasty with intraoperative anesthetic injection with 0.5% bupivacaine 20 ml dilute in 0.9%
Control group,Periarticular injection (PAI),Genicular infiltration
Sponsors
Nakornping Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 80 Years
Inclusion criteria
Inclusion criteria: patients who underwent simultaneous unilateral and bilateral total knee arthroplasty (TKA)
Exclusion criteria
Exclusion criteria: Contraindication for total knee arthroplasty from Thai OA knee guideline 2011 contra-indication for spinal anesthesia cognitive impairment patient Chronic renal disease (Creatinine clearance < 30 ml/min) Patients who are chronic alcohol users (defined as >1 drink per night for women or >2 drinks per night for men) Patients with poorly controlled diabetes mellitus (HbA1C >7.5 on preadmission testing) Patients with steroid or immunosuppressive drug use within 6 months of surgery Severe heart and liver disease Preoperative history of venous thromboembolism or deep vein thrombosis Patients with a hypercoagulable disorder Patients with a concurrent physical condition that may require analgesic treatment during study follow-up Allergy to drugs in the study chronic opioid used
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog pain score 4, 24, 48 hours, 2 weeks and 6 weeks postoperatively point/ ask patient give pain score in scale 0-10 point while they rest and on motion | — |
Secondary
| Measure | Time frame |
|---|---|
| extra dose opioid 24, 48 hours postoperatively miligram/ record from PCA chart,Time to first dose opioid 24 hours hours/ time zero is immediate post op to time that patient request IV opioid (while pain score more than 3),Length of stay 5 days days /time from admission to discharge,modified Thai WOMAC score 1 day before operation, 2 and 6 weeks after operation point/ ask patient and record in modified Thai WOMAC score chart then sum total score,Range of motion 1 day before operation, 24,48 hours, 2 and 6 weeks after operation degree/ used goniometer to measure range of motion from maximum extension to flexion | — |
Countries
Thailand
Contacts
Public ContactApisit Aoimoon
Nakornping Hospital
Outcome results
None listed