Reproductive age women who had intrauterine lesion that require Operative Hysteroscopy in office setting Misoprostol, Operative Hysteroscopy, office setting, visual analog scale
Conditions
Interventions
Misoprostol 200 mcg 1 tab vaginal suppository 12 hours before office operative hysteroscopy ,Vitamin B6 100 mg 1 tab vaginal suppository 12 hours before office operative hysteroscopy
Experimental Drug,Placebo Comparator Drug
Misoprostol group,Placebo group
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1 Women who had an appointment for operative hysteroscopy in outpatient department at ramathibodi hospital 2 age 18-50 years and in reproductive age 3 pelvic examination can done 4 BMI 18-30 kg/m2 5 Have confirm test from ultrasound or diagnostic hysteroscopy that have intrauterine lesion that require surgery such as endometrial polyp, myoma uteri size less than 3 cm., intrauterine adhesion, uterine septum, foreign body 6 Be willing to participate in the research and sign a consent letter
Exclusion criteria
Exclusion criteria: 1 Have contraindication for hysteroscopy such as pregnancy, pelvic inflammatory disease, suscepted cervical cancer or advance stage endometrial cancer 2 Underlying disease such as asthma, chronic kidney disease or hepatitis 3 Allergy to Misoprostol, NSIADs 4 Cervical stenosis or history cervical operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compared efficacy of the use of misoprostol to relieve pain during operative hysteroscopy in office setting compared with placebo During office hysteroscopy Visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Compared efficacy of the use of misoprostol to relieve pain before operative hysteroscopy in office setting compared with placebo Before office hysteroscopy Visual analog scale,Compared efficacy of the use of misoprostol to relieve pain during dilate cervix in operative hysteroscopy in office setting compared with placebo During dilate cervix Visual analog scale,Compared efficacy of the use of misoprostol to relieve pain during apply hysteroscopy into uterine cavity in operative hysteroscopy in office setting compared with placebo During apply hysteroscope Visual analog scale,Compared efficacy of the use of misoprostol to relieve pain 5 minutes after operative hysteroscopy in office setting compared with placebo 5 minutes after operative hysteroscopy Visual analog scale,Compared efficacy of the use of misoprostol to relieve pain 15 minutes after operative hysteroscopy in office setting compared with placebo 15 minutes after operative hysteroscopy Visual analog scale,Require for additional pain killer after each intervention After office hysteroscopy yes/no ,Comparison of duration of cervical dilatation During dilate cervix time,Comparison of duration of office hysteroscopy During office hysteroscopy time,Failure rate of office hysteroscopy During office hysteroscopy reteing of failure,side effect of Misoprostol drug After apply Misoprostol drug yes/no,Complication during the hysteroscopy During office hysteroscopy yes/no | — |
Countries
Thailand
Contacts
Public ContactNicharnart Pongsuttipanit
Faculty of Medicine Ramathibodi Hospital
Outcome results
None listed