Periodontally healthy Gingivitis Stage III Grade B periodontitis Periodontitis Gingivitis Saliva Interleukin-40 Interleukin-1 beta MMP-8
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. who had not received periodontal treatment and had not taken antibiotics in the last six months, 2. who did not have any systemic diseases affecting periodontal health, 3. aged between 18 and 65, 4. who did not smoke, 5. who were not pregnant, 6. who had at least 20 teeth, 7. voluntarily agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Those who have undergone periodontal treatment within the last 6 months for any reason, 2. Those who have used antibiotics in the last 6 months for any reason, 3. Those with any systemic disease known to affect periodontal health (heart disease, diabetes, blood diseases, etc.), 4. Those taking immunosuppressive medication, 5. Patients receiving chemotherapy or radiotherapy, 6. People with infectious diseases, 7. Pregnant women, 8. Smokers, 9. Those who do not want to participate in the survey
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| level of IL-40 in saliva after all saliva samples have been collected and analyzed We measured the clinical periodontal parameters and utilized the ELISA technique to detect the levels of IL-40 in the saliva samples. | — |
Secondary
| Measure | Time frame |
|---|---|
| level of IL-1 beta in saliva after all saliva samples have been collected and analyzed We measured the clinical periodontal parameters and utilized the ELISA technique to detect the levels of IL-1 beta in the saliva samples.,level of MMP-8 in saliva after all saliva samples have been collected and analyzed We measured the clinical periodontal parameters and utilized the ELISA technique to detect the levels of MMP-8 in the saliva samples. | — |
Countries
Turkey
Contacts
faculty member