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Effectiveness of combined a cognitive training exercise with non-pharmacologic interventions to prevent and reduce severity of delirium in critically ill surgical patients

Effectiveness of combined a cognitive training exercise with non-pharmacologic interventions to prevent and reduce severity of delirium in critically ill surgical patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230619002
Enrollment
164
Registered
2023-06-19
Start date
2023-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critically ill surgical patients cognitive training exercises, non-pharmacological, older, surgical patient, intensive care unit

Interventions

The Thai cognitive training exercises include non-pharmacologic (orientation, cognition, clearing eyes and ears, and pain control), digit span, digit game, memory task, blocks test, executive function
Experimental Other,No Intervention No treatment
Thai cognitive training exercises combine with non-pharmacologic,Usual care

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age of 65 years old or more 2.Patients undergoing surgery: general, cardiovascular and thoracic, vascular, urological, head and neck, orthopedic, gynecologic and obstetric 3. Anticipated LOS in SICU of more than 24 hours 4. A Richmond Agitation-Sedation Scale (RASS) score from -2 to +1 5. Hemodynamic stable: Systolic blood pressure (SBP) 90 to 180 mmHg, heart rate (HR) 60 to120 beats/min, the dose of norepinephrine less than 0.1 mcg/kg/min, and dopamine/dobutamine less than 5 mcg/kg/min 6. Respiratory system stability: positive end-expiratory pressure (PEEP) less than 10 cmH2O, and SpO2 more than 95%

Exclusion criteria

Exclusion criteria: 1. Patients who cannot communicate in the Thai language 2. Serious receptive aphasia or severe visual or auditory impairment that precludes communication 3. Severe cognitive impairment or who have a MOCA score of less than 10 4. Severe mental disability 5. Patients who have delirium on admission

Design outcomes

Primary

MeasureTime frame
feasibility of using Thai cognitive training exercises After 7 consecutive days in the ICU and Ward or untill hospital discharge Practicability and burden scores,incidence of delirium Daily assessment of delirium after SICU admission or until hospital discharge or death CAM-ICU and Nu-DESC test

Secondary

MeasureTime frame
duration of delirium Daily assessment of delirium after SICU admission or until hospital discharge or death CAM-ICU and Nu-DESC test,incidence of POCD Preoperative assessment and postoperative day 5 MOCA test,quality of life at hospital discharges EQ-5D-5L

Countries

Thailand

Contacts

Public ContactOnuma Chaiwat

Facuty of Medicine Siriraj hospital, Mahidol university

onuma.cha@mahidol.ac.th024197978

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026