Osteomyelitis of the mandible Osteomyelitis Mandible Reconstruction Immediate Delayed graft
Conditions
Interventions
En-bloc marginal resection will be performed to the normally bleeding bone followed by freeing the cut segment from the soft tissue coverage
to be removed. If IAN is encountered, it will be delicately freed from the cut segment. Immediate resection will be performed using bone block(s) from the anterior iliac crest and will be fixed in pla
Experimental Procedure/Surgery
primary reconstruction of osteomyelitis defects
Sponsors
Mosaad Khalifah
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1 Patients diagnosed with chronic suppurative osteomyelitis of the mandible based on the clinical picture (pain, tenderness, fever, lymphadenitis, painful or painless swelling, intraoral and or skin fistula(e), purulent discharge, hypoesthesia of the inferior dental nerve (IAN), and trismus), radiographic examination (moth-eaten appearance), and the histopathologic examination (necrotic bone, granulation tissue, inflammatory cells, and blood vessel thrombosis). 2 The proposed resection size be 6 cm or more; however, with the presence of sufficient mandibular bone at the inferior border of the mandible following the proposed marginal resection.
Exclusion criteria
Exclusion criteria: 1 The more extensive involvement of the mandible necessitating segmental resection 2 History of recent head or neck radiotherapy, concurrent head or neck radiotherapy, co-presence of malignancies, kidney-, liver-, or heart failure, any other bone marrow diseases, and immune diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| osteomyelitis eradication at 12 months eradicated/Not | — |
Secondary
| Measure | Time frame |
|---|---|
| graft success/failure at 12 months succeeded/Not | — |
Countries
Egypt
Contacts
Public ContactMosaad Kahlifah
Kafrelsheikh University
Outcome results
None listed