Healthy condition mung bean functional protein maximal oxygen consumption healthy volunteers
Conditions
Interventions
Subjects received the placebo product which has the same color and smell and looks like the functional drink.,Subjects receive the functional drink contain10 g of functional protein derived mung bean/
Placebo,the functional drink contain 10 g of functional protein derived mung bean,the functional drink contain 15 g of functional protein derived mung bean
Sponsors
FUNDAMENTAL FUND, Khon Kaen University
Eligibility
Sex/Gender
All
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Healthy volunteers between the ages of 45 and 60 years 2. Normal BMI <25 kg/m2 3. Do not consume drugs, health supplements or herbs, vitamins or minerals that have an ergogenic effect, not less than 2 months before joining 4. Can read and write Thai languages
Exclusion criteria
Exclusion criteria: 1. Have severe underlying diseases that require continuous medication, including cardiovascular disease, respiratory disease, Nervous system disease, diabetes, hyperlipidemia, High blood pressure, kidney disease, liver disease (assessed by AST or ALT is 2 times higher than normal (AST > 64 U/L; ALT > 50 U/L), lung disease or allergy, immune system disease, Hematologic disease, cancer, gout or high uric acid levels. 2. Have a history of food allergies to protein or nuts. 3. Have a regular consume of Probiotics such as yogurt, cheese, and kimchi etc. 4. Drink more than 5 alcoholic beverages per day. 5. Smoking more than 10 cigarettes per day. 6. Pregnant or planning to become pregnant at the time of the study or are breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the change in rate of Maximum aerobic oxygen consumption (VO2 max) Baseline, 6 week, and 12 week Fingertip Pluse Oximeter | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessed by the mechanical fitness test Baseline, 6 week, and 12 week the National Amateur Athletic Association. Japan Amateur Sports Association (JASA),Assess heart function and circulatory efficiency. Baseline, 6 week, and 12 week (Cardio-Vascular Test) using a hygroscopic test. Harvard Step Test (Harvard Step Test),Evaluate anaerobic performance using a running style test. Baseline, 6 week, and 12 week Direct (The repeated linear sprint test: RLST),Assess hemodynamics with pulse wave velocity, pulse wave analysis heart rate viability Baseline, 6 week, and 12 week SphygmoCor and Electrocardiogram (ECG),Evaluate Flow mediated dilation (FMD) before ingestion and at 30, 60 and 120 minutes after taking the product Flow mediated dilation (FMD),Take a daily energy intake assessment Baseline, 6 week, and 12 week 24-hour recall of food intake and a record of food intake and physical activity,Take a side effect assessment 6 week, and 12 week Record form,Safety parameters Hematology, Blood biochemical markers, Blood electrolytes, Hormones, Insulin, Blood Lactate Baseline, 6 week, and 12 week laboratory of hospital,acetylcholinesterase (AChE), Choline acetyltransferase (ChAT) monoamine oxidase (MAO; total MAO) Baseline, 6 week, and 12 week laboratory of HHP&HP,Oxidative stress status; malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) glutathione peroxidase (GPx Baseline, 6 week, and 12 week laboratory of HHP&HP,TNF, IL-6, NF-kB, nitrite, nitrate, uric acid, NO, AII, endothelin, Atherogenic index of plasma (AIP) Baseline, 6 week, and 12 week laboratory of HHP&HP,Genetic polymorphism Baseline, 6 week, and 12 week laboratory of HHP&HP,circulating histone, histone acetylase (HAT)histone deacetylase (HDAC), DNMT, histone acetylation Baseline, 6 week, and 12 week laboratory of HHP&HP | — |
Countries
Thailand
Contacts
Public ContactSuparporn Muchimapura
Faculty of Medicine, Khon Kaen University
Outcome results
None listed