Patients who needed a single-unit implant restoration with GBR of bony defects. Dental implants Hydroxyapatite Polycaprolactone
Conditions
Interventions
Commercial bovine bone graft + Commercial Collagen Membrane,Commercial bovine bone graft+Bilayered polycaprolactone membrane ,Polycaprolactone infiltrated porous nanohydroxyapatite bone graft + Commer
Commercial bone graft+Commercial Membrane,Commercial bovine bone graft+Bilayered polycaprolactone membrane ,Polycaprolactone infiltrated porous nanohydroxyapatite bone graft + Commercial Collagen Memb
Sponsors
Health Systems Research Institute (HSRI)
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients (age 20-65 years) 2. Good general health (ASA 1, 2) and not a contraindication for minor surgery 3. The diagnosis and indications for a particulate bone substitute are including: a. Alveolar bone defects, class 2. b. The edentulous area allows placement of at least one standard implant and not exceeded a two-tooth span. 4. Patients who needed reconstruction of the edentulous sites with simultaneous implant placement 5. Controlled periodontitis. 6. Smoking history less than 10 cigarettes per day. For the subject who smokes but less than 10 cigarettes per day is requested to stop smoking two weeks before and after bone block graft surgery and implant placement 7. No history of allergy or hypersensitivity to any of the materials to be used in the study.
Exclusion criteria
Exclusion criteria: 1. Presence of relevant medical conditions: Patients with bone disease, osteoporosis, uncontrolled diabetes mellitus, unstable or life-threatening conditions, or requiring antibiotic prophylaxis. Patients with medication of drugs influencing the bone metabolism or use of bisphosphonates. 2. Pregnancy or lactation. 3. Patients with active infection or pathologic lesions prior to operation 4. Patients who cannot take impression (both conventional and digital) and CBCT 5. History of malignancy, radiotherapy, or chemotherapy for malignancy in the past 5 years. 6. History of autoimmune disease or long-term prescribed of nonsteroidal antiinflammatory drugs 7. Unwillingness to return for the follow-up examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing 2 weeks, 1 month, and 3 months after the surgery. The healing index (HI),Implant stability 3 months, definitive restoration,6 months after surgery Radio Frequency Analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life Before surgery, 6 months after surgery Questionaire | — |
Countries
Thailand
Contacts
Public ContactJintamai Suwanprateeb
National Metal and Materials Technology Center
Outcome results
None listed