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Radiographic evaluation of alveolar ridge preservation using a chitosan/polyvinyl alcohol nanofibrous matrix: a randomized clinical study

Evaluating the Efficacy of Chitosan Nanofibrous Scaffold in socket Preservation After Tooth Extraction Randomized Controlled Clinical Study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230526005
Enrollment
12
Registered
2023-05-26
Start date
2022-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bone resorption following tooth extraction by measuring the linear radiologic changes vertically and horizontally as well as radiographic bone density by CBCT after 4 months. bone resorption socket preservation

Interventions

Chitosan/polyvinyl alcohol nanofibrous scaffold will be applied to the extraction socket, filled with blood, and sutured. then a CBCT is taken within 24 hours post-extraction (T0) and after 4 months.
Chitosan/Polyvinyl alcohol Scaffold,blood clot

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1 patient aged between 18-40 years old.2 Meet the ASA class I category.3 Not allergic to seafood or other components of the scaffolds used in this research.

Exclusion criteria

Exclusion criteria: 1 Patients with advanced and/or uncontrolled systematic diseases.2 Alcoholics. 3 Smokers. 4 Pregnant and lactating women. 5 Patients who are not willing to participate in this research.

Design outcomes

Primary

MeasureTime frame
linear vertical and horizontal bone height and width 4 months Linear measurement of bone height and width on CBCT

Secondary

MeasureTime frame
Radiographic Bone density 4 months Hounsfield Units in selected area (Region Of Interest) of CBCT.

Countries

Syrian Arab Republic

Contacts

Public ContactGamil ALMadhagy

Damascus University in syia

jimefara@gmail.com930664586

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026