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Pulpotomy vs Root Canal Treatment for Teeth with Symptomatic Irreversible Pulpitis: A Protocol for a Linked Series of Individual Randomised Control Trials and Prospective Meta-analysis

Pulpotomy vs Root Canal Treatment for Teeth with Symptomatic Irreversible Pulpitis: A Protocol for a Linked Series of Individual Randomised Control Trials and Prospective Meta-analysis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230526002
Enrollment
60
Registered
2023-05-26
Start date
2023-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

teeth with clinical diagnosis of symptomatic irreversible pulpitis symptomatic irreversible pulpitis coronal pulpotomy root canal treatment prospective meta-analysis

Interventions

Injection of local anaesthesia and rubber dam tooth isolation Disinfect the cavity prior to commencing caries excavation by wiping around the cavity with a 2 to 4 percent sodium hypochlorite solution
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
pulpotomy,root canal treatment

Sponsors

Faculty of Dentistry, Chiang Mai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients aged 12 years or older (with a mature permanent tooth with deep caries/restorations and symptoms indicative of IRP (moderate to severe spontaneous lingering pain). Tooth is responsive to cold and EPT sensibility testing, restorable and can be adequately isolated during treatment. One tooth (molar or premolar) per patient.

Exclusion criteria

Exclusion criteria: Teeth with active periodontal disease (pocket depth >5mm); teeth indicated for elective root canal treatment for restorative purposes, teeth with apical periodontitis, patients with complex medical histories that may affect their caries experience and healing ability (immunocompromised, radiotherapy etc.); patients who are unable to consent; history of trauma to the tooth, presence of apical radiolucency and patients who are pregnant or breast-feeding, any evidence of purulence or excessive bleeding that cannot be controlled with a cotton pellet with 2-4% hypochlorite for 10 minutes

Design outcomes

Primary

MeasureTime frame
success of treatment 1 year clinical and radiographic assessment

Secondary

MeasureTime frame
Quality of life 1 year Acceptance of participants

Countries

Thailand

Contacts

Public ContactPapimon Chompuinwai

Faculty of Dentistry, Chiang Mai University

papimon.c@cmu.ac.th0645164656

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026