Based on TCM theory, weakness of the spleen and stomach is the main cause of IBS-D, and spleen deficiency and dampness excess syndrome is a common type in clinical practice[16,17]. The therapeutic effect of moxibustion is mainly derived from the thermal effect of moxa burning on acupoints of body surface[18] and the chemical stimulation of drug components in moxa leaves[19,20], which can achieve the effect of invigorating spleen and dispelling dampness. Mild moxibustion is a complementary altern
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients should meet both TCM and Western diagnostic criteria of IBS-D; 2.Patients at age of 18 to 65 years old; 3.No history of relevant treatment before enrollment or with discontinuation of treatment with Chinese medicine, antidiarrheal drugs and antispasmodics for more than 1 month; 4.The total score of the IBS Severity Scoring System score(IBS-SSS) is more than 75; 5.Voluntary participation in this study and signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with IBS-C, IBS-M, and IBS-U; 2.Patients with inflammatory bowel disease, organic intestinal lesions, peptic ulcer, infectious diarrhea; 3.Patients combined with severe cardiovascular, hepatic, renal, endocrine and hematopoietic system diseases; patients with other diseases other than diarrhea that may affect the test results that cannot be discontinued; patients with mental illness; 4.Patients who are pregnant or lactating, and those who have a birth plan from their enrollment to 1 month after the end of the trial; 5.Those who have participated in other clinical trials within 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IBS-SSS 8 weeks includes five aspects with a score range of 0 to 100 out of 500 for each indicator | — |
Secondary
| Measure | Time frame |
|---|---|
| Irritable Bowel Syndrome-Quality of Life(IBS-QOL)score 8 weeks The score of Irritable Bowel Syndrome-Quality of Life | — |
Countries
China
Contacts
Changshu Hospital Affiliated to Nanjing University of Chinese Medicine