Dysmenorrhea is painful menses with cramping sensation in the lower abdomen that is often accompanied by sweating, headaches, nausea, vomiting, diarrhea, and tremulousness. Dysmenorrhea affects the quality of life of many women, school absenteeism or stopping their hobbies. So it has a negative impact on the quality of life and general health of women. The pain-relieving effect of Mefenamic acid, which is kind of non-steroidal anti-inflammatory drugs (NSAIDs) is reported on efficacy at approxi
Conditions
Interventions
The Leard ngam group will receive 2 capsules of 500 mg 3 times a day after meal on the first 3 days of the menstruation onset for 3 periods If the patient has a lot of pain She can take painkillers,Th
Active Comparator Drug,Active Comparator Drug
Leard ngam group,Control group
Sponsors
Chulabhorn International College of Medicine, Thammasat University
Arjaro Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 25 Years
Inclusion criteria
Inclusion criteria: 1 Female aged 18-25 years 2 BMI 18.5-22.90 3 Being Single 4 Suffers from primary dysmenorrhea (VMS grade 1-2, VAS level 1-7) and diagnosed by the gynecologist 5 Having regular menstrual cycle 6 Requires analgesic drug for relieving pain
Exclusion criteria
Exclusion criteria: 1 Pregnant or breastfeeding 2 Taking oral contraceptive medicine 3 Secondary menstrual cramps assessed by an obstetrician 4 Having severe gastrointestinal, gynecological, or autoimmune diseases 5 Receiving gynecological surgery within 1 year prior to the physical examination 6 Having medicinal and herbal sensitivities 7 Taking any other drugs apart from analgesic. 8. Taking dietary supplements such as evening primrose. 9. Having Blood diseases with disorders of the blood coagulation system and volunteers taking blood clot-dissolving drugs 10. Abnormalities are detected through physical examination, vital signs, heart rate, blood pressure. 11. Abnormal laboratory include biochemistry (electrolytes, liver function, kidney function, serum protein, lipid profile, uric acid), hematology (RBC, WBC, platelet counts), and urinalysis. 12. In the process of another research project
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Can Leard-ngam remedy relieve primary dysmenorrhea comparing with Mefenamic acid? VAS, VMS evaluated at baseline-3rd months of the study and 1st months after the end of the study , systemic symptoms evaluated at baseline and 1st months after the end of the study VAS, VMS, systemic symptoms | — |
Secondary
| Measure | Time frame |
|---|---|
| Can Leard-ngam remedy safe in relieving primary dysmenorrhea when compared with Mefenamic acid? at baseline and 3rd months of the intervention and adverse drug reaction was evaluated at 1st-3rd months of the intervention blood chemistry, liver function, renal function, adverse drug reaction | — |
Countries
Thailand
Contacts
Public ContactSunisa Leemud
Department of Thai Traditional and Alternative Medicine
Outcome results
None listed