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Comparing the effects of sevoflurane and desflurane on intracranial pressure in patients undergoing laparoscopic cholecystectomy via ultrasonographic measurement of the optic nerve sheath diameter: a randomized trial

Comparing the effects of sevoflurane and desflurane on intracranial pressure in patients undergoing laparoscopic cholecystectomy via ultrasonographic measurement of the optic nerve sheath diameter: a randomized trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20230511004
Enrollment
60
Registered
2023-05-11
Start date
2019-03-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who were scheduled for laparoscopic cholecystectomy Inhalational anesthesia and Intracranial pressure Desflurane laparoscopic cholecystectomy intracranial pressure optic nerve sheath sevoflurane ultrasonography

Interventions

Anesthesia was maintained by administering 1-2% sevoflurane in Group S,Anesthesia was maintained by administering 4-6 % desflurane in Group D
Diagnostic,Diagnostic
Group S,Group D

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: ASA 1-3 risk group patients who were scheduled for laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Those with a history of increased intracranial pressure, or with any condition that might cause an increase in intracranial pressure (ischemic cerebrovascular event, intracranial hemorrhage, brain tumor), those with eyeball diseases, glaucoma patients, those with a history of cataract surgery, and those under 18 years of age were excluded from the study.

Design outcomes

Primary

MeasureTime frame
intracranial pressure before anesthesia induction, 5 minutes after induction, 3 min after pneumoperitoneum, 20 min after pneumoperitoneum, 5 min after relasing pneumoperitoneum Optic nerve sheath diameter

Secondary

MeasureTime frame
mean blood pressure before anesthesia induction, 5 minutes after induction, 3 min after pneumoperitoneum, 20 min after pneumoperitoneum, 5 min after relasing pneumoperitoneum noninvasive

Countries

Turkey

Contacts

Public ContactMehmet Ozgur Inegol

University of Health Sciences Fatih Sultan Mehmet Health Application and Research Center

drozgurinegol@gmail.com902165783000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026