The effectiveness of intravenous dexamethasone prophylaxis before thyroidectomy in reducing postoperative pain, nausea and vomiting

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230510003

Enrollment

100

Registered

2023-05-10

Start date

2022-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients who underwent thyroid surgery in Hua Hin Hospital dexamethasone, postoperative pain, postoperative nausea and vomiting, effectiveness

Interventions

dexamethasone 8 mg intravenous,normal saline 2 mL intravenous

Experimental Drug,Placebo Comparator Drug

dexamethasone,normal saline

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients age 18-65 years who underwent thyroid surgery, 2. ASA class 1 or 2, 3. Ideal Body Weight 40-80 kilogram

Exclusion criteria

Exclusion criteria: 1. Patients with previous thyroid or neck surgery, 2. antiemetic consumption within 48 hours before surgery, 3. history of chronic pain, 4. history of DM or preoperative blood glucose more than 126 mg/dL, 5. history of postoperative nausea and vomiting, 6. pregnancy or lactation, 7. history of allergic reaction to medication used in this research, 8. history of underlying diseases that may be worsen by dexamethasone administration i.e. gastric ulcer

Design outcomes

Primary

Measure	Time frame
pain at 0, 1, 8 hours after surgery numerical rating scale	—

Secondary

Measure	Time frame
nausea and vomiting at 0, 1, 8 hours after surgery PONV score	—

Countries

Thailand

Contacts

Public ContactChernporn Payomyam

Hua Hin Hospital

chernporn048@gmail.com0859211606

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026