Effects of N-acetylcysteine supplementation on sperm quality and hormonal profile in idiopathic infertile men: before and after clinical trial

Status

Unknown

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230510002

Enrollment

Registered

2023-05-10

Start date

2022-10-03

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparison semen analysis and hormonal profile before and after NAC supplement Semen analysis, hormonal profile, NAC

Interventions

Oral NAC supplement 600 mg per day for 3 months.

Experimental Drug

NAC supplement

Eligibility

Sex/Gender

Male

Age

20 Years to 49 Years

Inclusion criteria

Inclusion criteria: male infertile never had child age 20-49

Exclusion criteria

Exclusion criteria: male infertile with known pathologic cause abnormal liver function smoking alcohol drinking habit abnormal male's reproductive system anatomy Klinefelter's syndrome fever 90 days before semen analysis history of liver cirrhosis history of peptic ulcer disease

Design outcomes

Primary

Measure	Time frame
semen quality 3 months semen analysis	—

Secondary

Measure	Time frame
hormonal profile 3 months hormonal profile	—

Countries

Thailand

Contacts

Public ContactKirana Benjamongkolchai

Bhumibol Adulyadej Hospital

bellnpc22@gmail.com0865154516

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026