Incidence of myocarditis and cardiac dysfunction in children with MIS-C was initially reported of 23-40%. While, the incidence of cardiac dysfunction or cardiovascular collapse associated with KD was reported as 5% in the 2017 KD guideline. However, long term data of detailed echocardiographic assessment of ventricular dysfunction, fate of coronary changes and MACE report in MIS-C is lack. MIS-C, Multisystem inflammatory syndrome in children, ventricular dysfunction, coronary artery, Kawasaki d
Conditions
Interventions
Pediatric patients who has been diagnosed with multisystem inflammatory syndrome in children (MIS-C),Pediatric patients who has been diagnosed with Kawasaki disease
Other,Other
MIS-C group,KD group
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
1 Months to 21 Years
Inclusion criteria
Inclusion criteria: 1. Pediatric patients who has been diagnosed with MIS-C or Kawasaki disease and regular follow up at Siriraj, Saraburi and Chonburi Hospital at least 1 year and 2. Echocardiographic examinations to assess LV function and coronary arteries were performed at the time of diagnosis, 2 weeks, 4-8 weeks following diagnosis, 1 year following diagnosis
Exclusion criteria
Exclusion criteria: Patients who had other congenital heart disease, myocardial disease, coronary anomaly, history of arrhythmia prior to diagnosis of MIS-C or KD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ventricular dysfunction 1 year echocardiographic assessment; EF strain, DD, 3D | — |
Secondary
| Measure | Time frame |
|---|---|
| coronary abnormality 1 year echocardiographic assessment: presence of coronary ectasia or aneurysms | — |
Countries
Thailand
Contacts
Public ContactChodchanok Vijarnsorn
Faculty of Medicine Siriraj Hospital
Outcome results
None listed