Skip to content

The effect of hyoscine butylbromide for shortening active phase of the first stage of labor : Double blind placebo-controlled trial

The effect of hyoscine butylbromide for shortening active phase of the first stage of labor : Double blind placebo-controlled trial

Status
Unknown
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230411002
Enrollment
120
Registered
2023-04-11
Start date
2022-07-02
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Singleton pregnancy in first stage of nplabor that plan vaginal delivery hyoscine butyl bromide duration of labor pregnancy

Interventions

hyoscine butylbromid injection when cervical dilatation 5-6 cm in low risk singelaton pregnancy that plan vaginal route delivery

Sponsors

khonkaen hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Singleton pregnant women >18 years old term pregnancy with a cephalic presentation and planned vaginal delivery

Exclusion criteria

Exclusion criteria: High risk pregnancy with contraindication to vaginal delivery e.g., placenta previa, Previous uterine surgery, Cephalopelvic disproportion Pregnancy women who received Epidural anesthesia. Pregnancy women with high risk for unstable fetal status e.g., Placental abruption, Meconium stained amniotic fluid, Fetal anomaly, Non reassuring fetal status Pregnancy women with contraindications for hyoscine-N-Butylbromide Pregnancy women who has infection, chronic disease or pregnancy- induced diseases e.g., Maternal fever (Body temperature more than 37.8 degree celcius), Thyroid disease, cardiovascular disease, Autoimmune disease, Gestational diabetes mellitus, Pregnancy induced hypertension.

Design outcomes

Primary

MeasureTime frame
Duration in active phase of. 1 stage of labor since intervention/control drug was injected until cervix dilated 10 cm duration time (minute)

Secondary

MeasureTime frame
Duration in second stage of labor since cervical fully dilate to fetus was deliveried Duration time (minute),duration in third stage of labor since fetus was deliveried until placenta was deliveried dutation time(minute),maternal adverse event since drug was injected until post partum 24 hr have/no have,neonatal outcome at 1,5 min APGAR score ,neonatal birth weight within 30 min after delivery grams,admission rate to nicu since birth until 24 hr post partum have/no have

Countries

Thailand

Contacts

Public Contactjongruk kamkong

khonkaen hospital

jongruk539@gmail.com0842266592

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026