1.Known hypersensitivity to dexamethasone. 2 .There are conditions that might influence gastrointestinal mobility including abdominal bowel surgery, previous abdominal irradiation. 3.Other gastrointestinal disorders (pancreatitis, peritonitis, hypothyroid, chronic use of opiate, musculoskeletal disorders and chronic use of drugs which impact intestinal peristalsis). 4.Patient underlying of diabetes who got poor control of glycemic control having HbA1Cmore than 8, moderate degrees of diabetic
Conditions
Interventions
1.Patients are eligible if they undergo a benign total abdominal hysterectomy with or without adnexal surgery. The patients are informed by researcher assistant about the study and ask for their conse
Experimental Drug
Dexamethasone
Sponsors
Khon Kaen Hospital Institute Review Board in Human Research
Eligibility
Sex/Gender
Female
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1.Women age >18 years old. 2.Patient who underwent benign total abdominal hysterectomy with or without adnexal surgery. 3.Patient who understands Thai language.
Exclusion criteria
Exclusion criteria: 1.Known hypersensitivity to dexamethasone. 2 .There are conditions that might influence gastrointestinal mobility including abdominal bowel surgery, previous abdominal irradiation. 3.Other gastrointestinal disorders (pancreatitis, peritonitis, hypothyroid, chronic use of opiate, musculoskeletal disorders and chronic use of drugs which impact intestinal peristalsis). 4.Patient underlying of diabetes who got poor control of glycemic control having HbA1Cmore than 8, moderate degrees of diabetic of retinopathy, impaired of visual acuity, history of wound resulting from diabetes at foot, history of foot amputation, claudication of lower limbs. 5.Patient who got immunocompromised host (Tubercolosis, Viral Infection) 6.Intraoperation blood loss of more than 1,000 ml or blood loss that requires blood transfusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PONV at 24 hours after surgery (n%) 24 hours after surgery Patient reported outcome using a questionnaire interview | — |
Secondary
| Measure | Time frame |
|---|---|
| Additional antiemetics requirements(n%) 24 hours after surgery Patient reported outcome using a questionnaire interview,Additional analgesic requirements(n%) 24 hours after surgery Patient reported outcome using a questionnaire interview,Side effects of dexamethasone(n%) 24 hours after surgery Patient reported outcome using a questionnaire interview,Analgesic effect measure by VAS mean(SD) 24 hours after surgery Patient reported outcome using Visual Analogue Scale,The duration of hospital stay (hours) mean (SD) 24 hours after surgery Patient reported outcome using a questionnaire interview | — |
Countries
Thailand
Contacts
Public ContactKanyawee Suhongsa
Khon Kaen Hospital
Outcome results
None listed