Cytomegalovirus anterior uveitis Cytomegalovirus anterior uveitis CMV Treatment outcomes Viral anterior uveitis
Conditions
Interventions
Patients who were treated with systemic ganciclovir (Intravenous or oral),Patients who were treated with 2% Ganciclovir ED or Ganciclovir gel
Treatment,Treatment
Systemic ganciclovir,Topical ganciclovir
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with signs and symptoms which are compatible with cytomegalovirus anterior uveitis 2. Patients with aqueous PCR positive for cytomegalovirus 3. Patients who was treated with topical or systemic ganciclovir
Exclusion criteria
Exclusion criteria: 1. Patients who were diagnosed as CMV intermediate uveitis or CMV retinitits 2. Patients who were diagnosed as uveitis from other causes e.g. Infection, Autoimmune disease, Idiopathic 3. Patients with aqueous PCR positive for other organism or mixed organism 4. Patients who were treated with combination therapy 5. Immunocompromised patients 6. Patients with age under 18 7. In case of failure in first treatment protocol and other treatments were introduced. Data collection will select only first treatment protocol as failure of treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response to treatment when response or failure to treatment was noted Percentage of response | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to response duration from starting of treatment to the time when resolution of A/C cell is documented duration from starting of treatment to the time when resolution of A/C cell is documented,Time to recurrence When next episode of inflammation happened uration from starting of treatment to the time when next episode of inflammation happened,Visual acuity When respond or fail to treatment Visual acuity measurement by ETDRS chart,IOP When respond or fail to treatment Air puff tonometer and Application tonometry | — |
Countries
Thailand
Contacts
Public ContactAssist. Prof. Sutasinee Boonsopon
Faculty of Medicine Siriraj Hospital Mahidol University
Outcome results
None listed