The pregnancy rate in embryo transfer needs to be improved. hCG subcutaneous injeciton may help to improve embryo implantation rate. frozen embryo transfer, hCG injection, pregnancy rate
Conditions
Interventions
standard luteal phase support using vaginal micronized progesterone,Subcutaneous injection of 250 microgram of hCG is provided at the night of commence of standard luteal phase support
standard luteal
standard treatment group,hCG group
Sponsors
Siriraj Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: infertile female who indicated for frozen embryo transfer age 18-40 years old has at least one good quality embryo frozen give consent to participate in the study
Exclusion criteria
Exclusion criteria: recurrent implantation failure (3 more times of embryo transfer) Uterine anomaly Endometrial pathology BMI>30 Thin endometrium
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemical pregnancy rate 2 weeks after embryo transfer serum hCG level | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation rate 4 weeks after embryo transfer Transvaginal ultrasound,Clinical pregnancy rate 4 weeks after embryo transfer Transvaginal ultrasound,ongoing pregnancy rate 12 weeks gestation Transvaginal ultrasound,first trimester miscarriage rate 12 weeks gestation Transvaginal ultrasound | — |
Countries
Thailand
Contacts
Public ContactIsarin Thanaboonyawat
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed