The efficacy of bile cell free DNA to diagnose cholangiocarcinoma in the patients with indeterminate biliary stricture without mass

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20230329004

Enrollment

Registered

2023-03-29

Start date

2023-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Indeterminate biliary stricture Cholangiocarcinoma Indeterminate biliary stricture Cholangiocarcinoma Bile cell-free DNA

Interventions

Patients with indeterminate biliary stricture due to inconclusive cytology and histopathology

Diagnostic

Indeterminate biliary stricture

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Indeterminate biliary stricture, determined as biliary stricture with inconclusive imaging study, cytology or histopathology

Exclusion criteria

Exclusion criteria: 1. Patients with known hepatobiliary cancer 2. Presence of pancreatic mass from imaging study (CT or MRI or ultrasound or EUS) 3. Uncorrectable coagulopathy 4. Patients with unstable vital signs

Design outcomes

Primary

Measure	Time frame
Cholangiocarcinoma 12 months Histopathology,Benign biliary stricture 12 months Histopathology	—

Secondary

Measure	Time frame
Sensitivity and specificity of bile cell free DNA 12 months DNA analysis	—

Countries

Thailand

Contacts

Public ContactWiriyaporn Ridtitid

Faculty of Medicine, Chulalongkorn University

wiriyaporn_r@yahoo.com022564265

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026