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The effect of probiotics supplementation in women with dysmenorrhea: a randomized controlled study

The effect of probiotics supplementation in women with dysmenorrhea: a randomized controlled study

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230326001
Enrollment
48
Registered
2023-03-26
Start date
2023-03-30
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

women with dysmenorrhea aged 18-24 years dysmenorrhea probiotics

Interventions

Participants in multispecies probiotics group received oral form once daily for 3 months. The placebo group received the oral form with identical sachets as the probiotics once daily for 3 months. Par

Sponsors

Ramathibodi hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 24 Years

Inclusion criteria

Inclusion criteria: 1 moderate dysmenorrhea 2 regular menstruation cycle 3 aged 18-24 years old 4 All patients need to write and sign a written informed consent.

Exclusion criteria

Exclusion criteria: Exclusion Criteria 1. Detecting a pathology in the pelvic organs from pelvic examination or ultrasound 2. History of other medical condition both acute and chronic diseases or have a congenital disease that requires regular medication including psychiatric diseases 3. Menstrual pain score less than 5 as assessed by VAS. 4. History of abdominal surgery 5. History of being diagnosed with a pelvic infection or sexually transmitted disease 5. History of using hormonal contraceptives or IUDs in the 6 months prior to study participation. 6 History of pregnant, miscarried, delivered a child, or were in the planning stages of pregnancy? 7. Take other dietary supplements, herbs, and vitamins 6 months before participating in the study. 8. Refusing to participate in a research project or withdrawing from the study. 9 .Have a history of allergy to powder or components of probiotics

Design outcomes

Primary

MeasureTime frame
dysmenorrhea 3 months Visual analogue scale

Secondary

MeasureTime frame
Frequency of Non-steroidal Anti-Inflammatory Drugs (NSAIDs) use between placebo and probiotic group 3 months number of tablets,quality of life 3 months questionnaire

Countries

Thailand

Contacts

Public ContactOrawin Vallibhakara

Faculty of Medicine, Ramathibodi Hospital, Mahidol University

orawinra38@gmail.com0942412229

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026