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Efficacy of topical local anesthetic, topical cooling spray, and audiovisual distraction on relief of needle-related pain during blood collection and blood donation

Efficacy of topical local anesthetic, topical cooling spray, and audiovisual distraction on relief of needle-related pain during blood collection and blood donation

Status
Unknown
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230324007
Enrollment
96
Registered
2023-03-24
Start date
2023-04-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Needle-related pain during blood sampling and blood donation Needle,Pain,Blood sampling,Blood donation

Interventions

Apply 1 gram of EMLA cream at the cubital area with occlusive for 1 hour then perform standard blood sampling/donation,Apply Topical cooling spray at the cubital area for 4-10 sec until the skin bec
Experimental Drug,Experimental Drug,Experimental Behavioral,No Intervention No treatment
topical local anesthetic,topical cooling spray,audiovisual distraction,Control

Sponsors

WU grant, Walailak University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Age 18-40 years old Volunteers receiving blood sampling and blood donation service Good consciousness

Exclusion criteria

Exclusion criteria: Mental retardation or unable to grading the pain score Volunteer being injected more than one time BMI more than 30 kg/m2 Unable to draw blood from veins in cubital area Allergic to local anesthetic, topical cooling spray Severe visual and auditory defects Psychiatric problems Abnormal Sensation at arms and forearms Unable to resist the cold environment Peripheral vascular disease, Raynaud disease, or Buerger disease Receiving analgesic drugs in past week Unable wait more than 1 hour (local anesthetic group)

Design outcomes

Primary

MeasureTime frame
Pain score less than 2 hr Numerical rating score

Secondary

MeasureTime frame
Pain score during needle was placed in vein for blood donation group less than 2 hours Numerical rating score

Countries

Thailand

Contacts

Public ContactSiwatus Puangrab

Walailak University

si_watus@hotmail.com0892036686

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026