Effectiveness of Lubrication of Laryngeal Mask Airway with Benzydamine Hydrochloride Spray versus Chamomile-Extract Spray for Prevention of Postoperative Sore Throat

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20230324005

Enrollment

228

Registered

2023-03-24

Start date

2022-08-19

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing surgery with general anesthesia with LMA. LMA, Postoperative sorethroat, Benzydamine Hydrochloride Spray, Chamomile-Extract Spray

Interventions

Four puffs of normal saline was sprayed on the LMA before inserting to the patients. ,Four puffs of 0.3% benzydamine hydrochloride spray was sprayed on the LMA before inserting to the patients.,Four

Placebo Comparator Drug,Active Comparator Drug,Active Comparator Drug

Control , 0.3% Benzydamine Hydrochloride Spray ,Chamomile-extract spray

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age 18-75 year ASA Physical status I-III Scheduled for GA with LMA

Exclusion criteria

Exclusion criteria: Contraindications for LMA Allergy to NSAIDs or Chamomile Pregnancy Postpartum less than 6 weeks Undergoing Neck, Head or C-spine surgery Recover from URI not more than 1 week On NG tube Surgery in lateral on prone position Operative time more than 3 hours Non-cooperative

Design outcomes

Primary

Measure	Time frame
Post operative sorethroat 1,4,24 hour post-operation 4 point scales	—

Secondary

Measure	Time frame
Side effect 1,4,24 hour post-opeation Symptoms of side effect	—

Countries

Thailand

Contacts

Public ContactPamanee Saimuey

Sakon Nakhon hospital

pamanee@hotmail.com042176000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026