Patients with melasma on both cheeks melasma, combination whitening cream, depiwhite
Conditions
Interventions
18 patients were treated with Depiwhite cream
Apply cream depiwhite 2 times a day for 1 month then once a day for 3 months + depiwhtie sunscreen. Then they were followed up after stop for 6 months,18 patients were treated with Depiwhite cream
Apply cream 2% hydroquinone onces a day for 1 month then once per two days for 3 months + depiwhtie sunscreen. Then they were followed up after stop for 6 months
combination whitening cream DEPIWHITE,2% hydroquinone cream
Sponsors
P.&.O. HEALTH CARE CO., LTD.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-60 years 2. Have melasma on both cheeks
Exclusion criteria
Exclusion criteria: 1. Patients having infection or active wound in the test area 2. Taking oral or topical whitening agents within 1 month or laser or melasma treatment within 6 months prior to inclusion 3. Allery to alpha-hydroxy acid, antipollon, phosphatase activators, vitamin PP, kojic acid, vitamin C, arbutin, luteoline and parsley 4. Pregnancy 5. Taking oral antioxidants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma severity baseline, 1 month, 3 months, after stop treatment at 1 & 3 & 6 months mMASI score | — |
Secondary
| Measure | Time frame |
|---|---|
| Melanin index and Erythema Index baseline, 1 month, 3 months, after stop treatment at 1 & 3 & 6 months Mexameter,Physician assessment baseline, 1 month, 3 months, after stop treatment at 1 & 3 & 6 months Quatile scale,Patient Assessment baseline, 1 month, 3 months, after stop treatment at 1 & 3 & 6 months VAS,Safety baseline, 1 month, 3 months, after stop treatment at 1 & 3 & 6 months Adverse events | — |
Countries
Thailand
Contacts
Public ContactSasima Eimpunth
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed