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Efficacy of Different Frequency of Daily Saline Irrigation in Postoperative Endoscopic Sinus Surgery: A randomized controlled trial

Efficacy of Different Frequency of Daily Saline Irrigation in Postoperative Endoscopic Sinus Surgery: A randomized controlled trial

Status
Unknown
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230321009
Enrollment
80
Registered
2023-03-21
Start date
2023-04-17
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The chronic rhinosinusitis with and without nasal polyp patients who undergo full-house ESS. Chronic rhinosinusitis Endoscopic sinus surgery Postoperative care Saline irrigation

Interventions

The patients will receive saline irrigation after endoscopic sinus surgery twice a day, 125 mL per each nose and time for one month. ,The patients will receive saline irrigation after endoscopic sinu
Postoperative saline irrigation two times per day.,Postoperative saline irrigation four times per day

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: The CRS with and without nasal polyp patients who undergo full-house ESS aged more than 18 years old or older.

Exclusion criteria

Exclusion criteria: The exclusion criteria are the patients who use the non-absorbable nasal packing at the end of operation in order to control postoperative hemostasis or as a spacer to stabilize the middle turbinate and the patients who have postoperative bleeding and need furthermore nasal packing or reoperation to stop bleeding during the follow-up periods. The patients who have complicated sinusitis, intraoperative surgery beyond the full-house ESS and patients who have to avoid postoperative saline irrigation such as CSF leak.

Design outcomes

Primary

MeasureTime frame
SNOT-22 score At 1, 2 and 4 weeks postoperative SNOT-22 score

Secondary

MeasureTime frame
LKES score At 1, 2 and 4 weeks postoperative LKES score ,POSE score At 1, 2 and 4 weeks postoperative POSE score ,VAS score of sinonasal symptoms At 1, 2 and 4 weeks postoperative VAS score of sinonasal symptoms,Side effects (burning sensation and ear fullness/pain ) At 1, 2 and 4 weeks postoperative Categorical outcome

Countries

Thailand

Contacts

Public ContactKangsadarn Tanjararak

Faculty of Public Health, Khon Kaen University

kang006611@gmail.com0839166638

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026