Older asthmatic patients with stable treatment Older subjects with healthy or stable diseases other than asthma Asthma IL17 Polymorphism Phenotype
Conditions
Interventions
Asthmatic patients aged 60 years or older,Heathy subjects or patients with stable diseases
Basic Science,Basic Science
Asthma group,Control group
Sponsors
Faculty of Medicine, Thammasat University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Asthmatic patients aged 60 years or older with stable treatment, 2. Subjects aged 60 years or older with healthy or stable diseases other than pulmonary diseases
Exclusion criteria
Exclusion criteria: 1. Smoking history 10 pack-years or more, 2. inability to perform spirometry, 3. asthma exacerbation within 3 months, 4. Treatment with systemic corticosteroid within 3 months, 5. Pulmonary diseases other than asthma eg.COPD, bronchiectasis, pulmonary fibrosis, 6. Autoimmune diseases eg. SLE, Rheumatoid arthritis, 7. Cancers, 8. Coronary heart diseases, 9. Cerebrovascular disease including stroke and dementia, 10. Uncontrolled chronic diseases eg, DM, HT, liver cirrhosis, CKD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abnormal IL17 polymorphism At the begin of the study Percentage,Phenotypes At the begin of the study Percentage | — |
Secondary
| Measure | Time frame |
|---|---|
| FEV1 At the begin of the study Percentage,FeNO level At the begin of the study ppb,Absolute eosinophil counts At the begin of the study cells/microliter | — |
Countries
Thailand
Contacts
Public ContactNarongkorn Saiphoklang
Faculty of Medicine, Thammasat University
Outcome results
None listed