Vascular Mild Cognitive Impairment among Post-Stroke Patients Stroke, Vascular Mild Cognitive Impairment
Conditions
Interventions
The stingless bee honey (SBH)-supplemented group will be supplemented with 20g of SBH daily for three months via oral administration.
Experimental Dietary Supplement
Stingless bee honey (Trigona spp)
Sponsors
Universiti Sains Malaysia
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Confirmed Acute Ischemic stroke patients based on clinical and radiological features (American Heart Association (AHA)/American Stroke Association (ASA) definition). 2. Age between 40-80 years old. 3. Hospitalized within 72 hours after the acute stroke. 4. A stroke patient with mild to severe VCI determined by Montreal Cognitive Assessment (MoCA) score (<26/30).
Exclusion criteria
Exclusion criteria: 1. History of progressive cognitive impairment or dementia prior to the current stroke. 2. Severe aphasia based on the National Institutes of Health Stroke Scale (NIHSS). 3. Uncontrolled Diabetes Mellitus (DM) with capillary blood glucose persistently more than 10 mmol/L 72 hours after stroke onset. 4. Severe stroke, comatoseness, or any condition precludes patients from answering the MoCA test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function before intervention and at three month after end of intervention Montreal Cognitive Assessment Test | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood biomarkers serum samples collected from before intervention and at three month after end of intervention Enzyme-linked immunosorbent assay (ELISA) | — |
Countries
Malaysia
Contacts
Public ContactSabarisah Hashim
Universiti Sains Malaysia
Outcome results
None listed